Yadier Molina grounded an RBI single down the third base line in the ninth inning and the St. Louis Cardinals edged the Miami Marlins 1-0 Wednesday to sweep the season series.

Molina's eighth career regular season walk-off hit came with one out and sent Miami to its fourth straight loss.

Paul Goldschmidt reached on an error by shortstop Jazz Chisholm Jr. to start the ninth. After Matt Carpenter walked with one out, Molina singled off Marlins starter Sandy Alcantara (4-6).

The Cardinals went 6-0 against Miami this year for their first season sweep over the Marlins. St. Louis won all three games at Busch Stadium in its final at-bat - Goldschmidt's solo homer in the ninth produced a 2-1 win Tuesday night.

Ryan Helsley (4-4) and Andrew Miller combined for two scoreless innings of relief.

Cardinals starter Johan Oviedo is still seeking his first major league win despite pitching a career-high seven scoreless innings. The right-hander allowed six hits, struck out four, walked none and 63 of his 87 pitches were strikes.

Alcantara pitched a team season-high 8 1/3 innings. He gave up six hits, struck out seven with one walk, and the one run he allowed was unearned.

Oviedo retired the first 10 batters he faced before giving up back-to-back singles to Jon Berti and Jesus Sanchez in the fourth. Goldschmidt made a strong throw home to Molina on a grounder by Jorge Alfaro to get Berti at the plate.

A throwing error and a botched fielder's choice by the Marlins defense put Alcantara into a jam in the fourth, but he got out of it by getting Edmundo Sosa to hit into a double play.

Alcantara finished at 108 pitches, 76 for strikes.

Marlins manager Don Mattingly didn't hesitate to send Alcantara back out for the ninth inning.