Kris Bryant, Anthony Rizzo and David Bote homered, Trevor Williams pitched effectively into the seventh inning, and the Chicago Cubs beat the Arizona Diamondbacks 5-1 on Sunday.

Bryant and Bote each hit two-run shots as Chicago took two of three in the series.

Williams (4-2) struck out six and allowed five hits with no walks over 6 1/3 innings in his first scoreless outing of the season. It was the right-hander's second start (and third appearance) since missing five weeks following an appendectomy.

After Willson Contreras led off the bottom of the first with a walk, Bryant stroked an 0-1 pitch into the center-field bleachers. It was Bryant's 17th homer and first since July 3. He is one of several Chicago players who could be traded before Friday's deadline.

Rizzo followed with a solo shot for a 3-0 lead. It was his 240th homer with the Cubs, passing Aramis Ramirez for sixth place on the team's career list.

Craig Kimbrel, another likely trade target, came on to get the final out for his 23rd save.

Kyle Hendricks (12-4, 3.61) looks to become the first 13-game winner in the majors Monday night in the opener of a four-game home series with Cincinnati. LHP Wade Miley (8-4, 2.72) starts for the Reds.