Wander Franco hit his first homer of the season, a two-run drive to left-center in the third inning, and the Tampa Bay Rays held on to beat the Chicago Cubs 6-5 on Tuesday night.

Cubs rookie Seiya Suzuki drew three walks but his nine-game hitting streak came to an end, leaving him tied with Akinori Iwamura for the longest hitting streak by a Japanese-born player to start a career.

Playing at Wrigley Field for the first time, Franco finished 3-for-5, including the homer that put the Rays ahead 3-0. The second-year player missed Monday's series opener with right quadriceps tightness.

Franco's three-hit game was his fourth of the young season.

Opener Matt Wisler got the first five outs for the Rays and Josh Fleming (2-1) worked the next 3 1/3 innings, allowing three runs on four hits. Andrew Kittredge, the sixth Rays pitcher, retired the final six Chicago batters for his second save. He needed just 20 pitches to do it.

Justin Steele (1-1) allowed four runs in 2 2/3 innings.

Patrick Wisdom hit a two-run, pinch-hit homer in the fourth inning to get the Cubs within 4-3. Chicago had won two straight.

Manuel Margot had an RBI single in the second for the Rays, and Tampa Bay went ahead 6-3 in the seventh on run-scoring hits from Randy Arozarena and Harold Ramirez.

Nico Hoerner had an RBI triple in the seventh and scored on a wild pitch to get the Cubs within one run again.

Tampa Bay's Drew Rasmussen (0-1, 5.00 ERA) faces Marcus Stroman (0-1, 6.00) in Wednesday's series finale.