Giannis Antetokounmpo had 33 points and nine rebounds and the Bucks routed the Bulls 116-100 on Wednesday night to finish off their first-round series in five games.

The Bucks won the last three games by an average of 23.3 points despite playing without Khris Middleton, the All-Star who sprained the medial collateral ligament in his left knee during the fourth quarter of Game 2.

The third-seeded Bucks advanced to face second-seeded Boston in the Eastern Conference semifinals, with Game 1 on Sunday in Boston. The Celtics swept Brooklyn.

The Bulls played without the starting backcourt they used for the first four games because two-time All-Star Zach LaVine was in health and safety protocols and Alex Caruso was in concussion protocol. Without them on the floor, the Bulls fell behind by as many as 29 points in the first half.

Milwaukee focused on containing DeRozan, who had scored 41 points in the Bulls' Game 2 victory. DeRozan was held to 11 points Wednesday while shooting 5 of 10, though he also had seven assists.

Antetokounmpo was 1 of 15 from the floor and 11 of 14 from the free-throw line. Pat Connaughton went 6 of 9 on 3-point attempts and scored 20 points. Bobby Portis added 14 points and a career-high 17 rebounds.

Patrick Williams scored 23 points, Nikola Vucevic 19 and Coby White 17 for the Bulls. Vucevic also had 16 rebounds and six assists.

DeRozan was scoreless in the first 26 minutes of the game and attempted just one shot in the first quarter as he tried to get his teammates involved.

The problem was Chicago's other players weren't hitting open shots, allowing the Bucks to take command early.

Milwaukee pulled ahead for good 3 1/2 minutes into the game and built a double-digit lead by scoring 12 straight points in the first quarter. Late in the first period, the Bucks began a 23-2 run that helped them extend the advantage to 49-20 with 7:25 left in the second period.

Chicago outscored the Bucks 22-11 the rest of the second quarter and got the margin down to 11 on Ayo Dosunmu's 3-point play with 9:32 left in the third quarter, but that's as close as the Bulls would get.

The Bulls attempted 52 shots from 3-point range and only 40 from inside the arc. Chicago made just 28.8% of its 3-point shots. 

The Bulls haven't advanced beyond the first round of the playoffs since 2015, when they beat the Bucks before losing to the Cleveland Cavaliers in the East semifinals.  
With LaVine and Caruso unavailable, Javonte Green and Dosunmu made their first career playoff starts.