Eastern Illinois scored all its points in the first quarter and the Panthers intercepted three passes to beat Lindenwood 16-10 on Saturday.
A Stone Galloway field goal, Eli Mirza's 38-yard touchdown reception from Pierce Holley and MJ Flowers' 4-yard rushing score gave the Panthers all their points.
The Lions got a Logan Seibert field goal in the second quarter but didn't score again until Chase Lanckriet caught a 10-yard TD from Cooper Justice with 1:19 remaining.
Holley was 18-of-34 passing for 245 yards, one touchdown and one interception.
The victory ensured the first winning season for Eastern Illinois (6-3, 2-2 Big South-OVC Association) since 2017.
Two quarterbacks combined to go 20 of 33 for 249 yards passing for the Lions (3-6, 1-4).