Actor Rob Lowe is causing the rumor mill to swirl over tweets that Colts quarterback Peyton Manning will retire. Lowe posted on Twitter, "Hearing my fave, #18 Peyton Manning will not return to the NFL. Wow." He added, "Colts fans, let's hope my info is wrong. Don't like being wrong, but this time...I'm hoping." Lowe is a friend of Manning's and has been on the sidelines for Colts games in the past. The 35-year-old Manning missed all of this season recovering from offseason neck surgery. The Colts are expected to take Stanford quarterback Andrew Luck with the first pick in the April NFL Draft.