The Colts have claimed guard Donovan Williams off waivers from Chicago and placed punter Michael Palardy on waivers.
Starting guard Denzelle Good and backup offensive lineman Kevin Graf both were injured in Saturday night's 19-18 victory at Buffalo.
The 6-foot-3, 315-pound Williams signed with Chicago as an undrafted rookie out of Louisiana-Lafayette in May. He was waived by the Bears on Saturday.
Palardy signed with the Colts on Aug. 6 after Pro Bowl punter Pat McAfee hurt his knee at training camp. He also has spent time with Baltimore, Carolina, Oakland and the St. Louis Rams but never appeared in an NFL game.