Antonio Brown hauled in three touchdown catches of more than 20 yards to give the Pittsburgh Steelers a 28-7 victory over a depleted Colts team that was missing star quarterback Andrew Luck.
Brown took full advantage of his chances by scoring on three of his five catches and finishing with 91 yards, two short of joining Hines Ward as the only receivers in franchise history with four straight 1,000-yard seasons.
Brown has 23 receptions for 342 yards and seven TDs in three career games against the Colts.
The Steelers built a 21-7 lead by scoring touchdowns on each of their first three possessions - a 5-yard run from Le'Veon Bell, and touchdown catches by Brown of 25 and 33 yards.
Indy's only score came on a 5-yard TD pass from Tolzien to Donte Moncrief early in the second quarter, a play set up by the first completion of Pat McAfee's career on a fake punt.
The Colts (5-6) had two chances to trim the deficit but Tolzien was stopped twice on third-down runs at the 1-yard line, and the Steelers forced incompletions on both fourth-down plays.
Bell ran 23 times for 120 yards.
Tolzien finished 22 of 36 for 205 yards with one TD and two interceptions.
Steelers: Will try to extend their winning streak to three Dec. 4 when the New York Giants visit.
Colts: Hope to have Luck back in the lineup when they visit the New York Jets on Dec. 5.