Ryan LaMarre's line drive to left field bounced off the top of the bullpen shelter and into the hands of a familiar face, as LaMarre's uncle made the catch.

 

LaMarre, who hit the homer in his 168th plate appearance, acknowledged hitting one to a family member was a longshot.

 

The home run gave the White Sox a 4-3 lead in the second inning, and Lucas Giolito pitched out of a bases-loaded, no-out jam in the sixth inning as the White Sox held on to win 6-3.

 

Chicago won for the second time in eight games, improving to 2-9 against Detroit this season.

 

Giolito (8-9) allowed three runs and eight hits and one walk in six innings. He struck out seven to improve to 3-1 in his past six starts.

 

The Tigers got runners to the corners in the ninth, but Xavier Cedeno struck out Nicholas Castellanos to earn his first save since Aug. 11, 2015.

 

Blaine Hardy (4-5) took the loss, allowing four runs and six hits and a walk in four innings.

 

Both teams scored three runs in the first inning, Chicago getting its final two on a bizarre play. Daniel Palka's RBI single made it 1-0 and left the bases loaded with one out. Kevan Smith hit a fly ball to deep center, and all three runners tried to advance.

 

Palka stopped between first and second as Jose Abreu scored from third, and by the time the Tigers were able to finish off a sloppy rundown, Matt Davidson had scored from second for a two-run sacrifice fly double play as Palka was thrown out at second to end the inning.

 

In the bottom of the first, Victor Martinez made it 3-2 with a two-out, two-run double, and Jim Adduci followed with a game-tying single. The Tigers, though, never scored again.

 

LaMarre put Chicago back ahead with his family-finding line drive.

 

Zach McAllister replaced Hardy for the fifth inning, and the White Sox quickly took advantage. Tim Anderson and Avisail Garcia led off with singles, and Abreu made it 6-3 with a two-run double.

 

The Tigers loaded the bases with no outs in the sixth, but Giolito got out of it when James McCann popped out, Mike Gerber struck out and Victor Reyes popped out.

 

Renteria had relievers ready, but gave his starter a chance to save the game.

 

The teams finish the three-game series on Wednesday afternoon. Detroit's Jordan Zimmermann (5-4, 3.98 ERA) will face Carlos Rodon (3-3, 2.61).