Carson Edwards scored 23 points on 8-of-14 shooting after making 7 of his 40 attempts in the previous two games, and Purdue got its fourth straight victory, 73-56 over Illinois.
Matt Haarms had 21 points on 8-of-8 shooting, 10 rebounds and five blocks for the Boilermakers (21-7, 14-3 Big Ten), who moved into a tie atop the conference with No. 6 Michigan State.
Illinois (10-18, 6-11) led the back-and-forth game 33-32 at halftime and rallied to tie it at 48 with 9:43 remaining. Then Edwards and Haarms took over as the Boilermakers scored 12 straight points.
Illinois got no closer than nine points the rest of the way.
Haarms found an advantage over Illinois center Giorgi Bezhanishvili, who was hampered by foul trouble most of the night. Bezhanishvili recorded just two points and five rebounds before fouling out.
Illinois struggled from the field, shooting 32.8 percent overall and 27.6 percent from 3-point range.
Ayo Dosunu and Andres Feliz led Illinois with nine points apiece. The Boilermakers held a 36-27 advantage on the boards.
Illinois hosts Northwestern on Sunday.
>>Illinois State Rolls Missouri State
Milik Yarbrough had 28 points as Illinois State topped Missouri State 65-57 on Wednesday night.
Yarbrough converted all 11 of his free throws. He added nine rebounds.
Phil Fayne had 18 points and seven rebounds for Illinois State (16-14, 9-8 Missouri Valley Conference).
Keandre Cook had 16 points for the Bears (16-14, 10-7). Jarred Dixon added 15 points. Tulio Da Silva had 12 points and 11 rebounds.
The Redbirds leveled the season series against the Bears with the win. Missouri State defeated Illinois State 66-65 on Feb. 10.
Illinois State finishes out the regular season against Southern Illinois on the road on Saturday.
>>Bradley Topples Valpo
Nate Kennell had a season-high 20 points as Bradley rolled past Valparaiso 67-42 on Wednesday night.
Elijah Childs had 18 points and eight rebounds for Bradley (17-13, 9-8 Missouri Valley Conference), which earned its fourth consecutive home victory. Darrell Brown added 10 points. Dwayne Lautier-Ogunleye had eight rebounds and seven assists for the home team.
The Crusaders' 26.8 field goal percentage represented the worst mark by a Bradley opponent this season.
Valparaiso put up 20 points in the second half, a season low for the team.
Derrik Smits had 12 points for the Crusaders (14-16, 7-10). Javon Freeman-Liberty added seven rebounds. John Kiser had seven rebounds.
The Braves leveled the season series against the Crusaders with the win. Valparaiso defeated Bradley 61-50 on Jan. 8. Bradley finishes out the regular season against Loyola of Chicago on the road on Saturday.