Danilo Gallinari scored 24 points, Montrezl Harrell had 20 points and 12 rebounds, and the Clippers beat Indiana 115-109 on Tuesday night, preventing the Pacers from clinching a playoff berth.
Clinging to a 110-107 lead, Lou Williams hit a pullup jumper with 40 seconds left to stop a 5-0 run by Indiana.
Tyreke Evans answered with a layup that again drew the Pacers within three.
After a timeout, Bojanc Bogdanovic slipped defending Patrick Beverley, who scored and then made a rolling dice motion.
Bogdanovic slipped again on the Pacers' final possession and they failed to score over the final 33 seconds.
Evans and Bogdanovic scored 19 points each for the Pacers, whose road skid extended to seven straight games. Doug McDermott added 17 points and Domantas Sabonis had 13 points and a career-high-tying 16 rebounds playing the second night of a back-to-back.
The Clippers led by 17 early in the fourth only to see the Pacers close within five. Gallinari re-entered the game and promptly hit a 3-pointer that ended Indiana's 16-7 run.
Beverley made a 3-pointer and Gallinari and Gilgeous-Alexander combined to make four straight free throws that extended the Clippers' lead to 106-97.
Los Angeles closed the third by scoring eight straight points to lead 89-75 going into the fourth.
The Pacers visit Golden State on Thursday to end four-game Western swing.