Seth Curry scored a season-high 20 points and the Trail Blazers beat the Chicago Bulls 118-98 on Wednesday night.
Still shaken by Jusuf Nurkic's gruesome leg injury two nights earlier in a double-overtime victory over Brooklyn that secured their sixth straight playoff appearance, the Blazers made it look easy against a short-handed team.
Curry made four 3-pointers, Rodney Hood added 15 points, and Enes Kanter and Zach Collins each had 13. Portland won its fifth in a row even though Damian Lillard scored a season-low 11.
Chicago's Shaquille Harrison set career highs with 21 points and 10 rebounds. Robin Lopez had 15 points and nine rebounds. But with mostly reserves in the lineup, the Bulls lost for the eighth time in 10 games.
Chicago announced afterward forward Lauri Markkanen will miss the remainder of the season after experiencing a rapid heart rate and fatigue.
Markkanen joins a long list of unavailable Bulls players. Wendell Carter Jr., Chandler Hutchison and Denzel Valentine all had season-ending injuries.
Leading scorer Zach LaVine (bruised right thigh, right knee tendinitis), Otto Porter Jr. (strained right rotator cuff) and Kris Dunn (back) were unavailable Wednesday.
The Bulls host Toronto on Saturday night.