Jake Arrieta allowed one run over six innings in his return to Wrigley Field, J.T. Realmuto hit a solo homer in the 10th and the Philadelphia Phillies beat the Chicago Cubs 5-4 on Monday.
Realmuto connected with two outs against Kyle Ryan (0-1), driving a 1-2 fastball a few rows into the left-field seats to decide the opener of a four-game series between the NL East and Central leaders. But the night belonged to Arrieta.
Hector Neris (1-1) worked a scoreless ninth. Adam Morgan struck out Jason Heyward leading off the 10th, and Juan Nicasio earned his first save since last June 28 when he got Daniel Descalso to ground into a double play after giving up a single to Albert Almora Jr.
Philadelphia scored three runs with two outs in the sixth against Darvish for a 3-1 lead. Realmuto hit an RBI single, and Cesar Hernandez followed with a two-run triple to right that ricocheted off the side wall and bounced over Heyward's head.
The Cubs scored three in the eighth against Seranthony Dominguez. Descalso drove in two with a triple to left-center, then was rewarded home when the relay from shortstop Jean Segura ricocheted off his right foot and into Chicago's dugout.
Philadelphia tied the game in the ninth against Brad Brach when Maikel Franco doubled and came home on a two-out bloop single to right by Segura.
Darvish gave up three runs, four hits and three walks in six innings while striking out seven.
Anthony Rizzo had three hits, including an RBI single.
Zach Eflin (5-4, 2.89 ERA) tries for his fourth win in five starts.
Jose Quintana (4-3, 3.68) has lost two straight starts after going 4-0 in his previous five.
Jake Marisnick and Tyler White homered and Brad Peacock had another solid start to lead the
Astros over the Chicago White Sox 3-0.
With George Springer, who leads the American League with 17 homers, out with a stiff back the Astros got pop from the bottom of the lineup to give them at least one homer in 17 straight games.
They have 40 home runs in that span, and the two long balls Monday night helped them to their 11th
win in 12 games.
Peacock (5-2) allowed two hits and fanned nine in five innings for his third straight win. He has allowed just two runs combined in his last three starts after giving up 11 combined in his previous three outings.
Ryan Pressly pitched a scoreless eighth to extend his MLB-record streak of appearances without allowing a run to 40, and Roberto Osuna gave up a hit in the ninth, preserving the shutout and earning his 12th save.
The White Sox used five pitchers on a bullpen day which began with Ryan Burr (1-1), who had made 22 relief appearances in two seasons with the team, but whose last start came at Arizona State on Feb. 23, 2014. He allowed one hit and one run - which was unearned, in two innings.
Eloy Jimenez was reinstated from the 10-day injured list before Monday's game, taking the roster spot of OF Nicky Delmonico, who was optioned to Triple-A Charlotte on Sunday. Jimenez has been on the injured list since April 28 after sustaining a high ankle sprain two days earlier.
Dylan Covey (0-2, 4.41 ERA) will start for Chicago on Tuesday. Covey did not factor in the decision after allowing two hits and two runs in 5 2/3 innings against Toronto in his last start.
Justin Verlander (7-1, 2.38) is scheduled to start for Houston on Tuesday. Verlander yielded two hits and one run in seven innings against Detroit for his third straight win the last time out.