Pablo Sandoval homered with one out in the 13th inning, sending the San Francisco Giants past the Chicago Cubs 5-4 on Tuesday night long after Bumgarner's night was done.

Sandoval just cleared the left-field fence with his first-pitch drive off Brad Brach (3-3) that went to replay and was upheld to formally finish the 3-hour, 45-minute game.

Sam Coonrod (1-0), San Francisco's fifth reliever, pitched the 13th for his first career victory. The Giants had missed a chance in the 10th when Sandoval grounded out with the bases loaded.

Madison Bumgarner struck out seven over seven innings in another strong start without a win to show for it, then San Francisco won playing its fifth extra-inning game in the last eight and fourth of the homestand. The Giants had a 16-inning victory Bumgarner's last time out.

Jason Heyward hit a tying single in the eighth for the Cubs, who have lost 10 of the last 14 in San Francisco.

Bumgarner, 9-2 in 14 career starts against the Cubs, dueled with Yu Darvish after the Cubs right-hander had worked six scoreless innings in each of his past two outings.

Kris Bryant hit a pair of RBI singles for the Cubs. He singled in the first as the Cubs went ahead only for San Francisco to tie it in the second on Mike Yastrzemski's sacrifice fly.

Bryant singled again in the third before Alex Dickerson tied it at 2 with a solo homer in the fourth. Kevin Pillar then hit a go-ahead two-run double three batters later.

Jon Lester (9-6, 3.87 ERA) is coming off a no-decision last Friday against the Padres in which he was tagged for 12 hits, matching the most he has allowed in his career. He is 5-1 with a 2.00 ERA in six career regular-season starts against the Giants.

Giants starter Tyler Beede (3-3, 4.70) owns a 1.66 ERA in July. The right-hander will face the Cubs for the first time having pitched a career-high eight innings Friday against the Mets.