Kyle Lowry had 16 points and 11 assists, extending his career-best streak of double-doubles to six, and Toronto hammered Indiana 127-81 on Sunday, the most lopsided victory in Raptors history.

Pascal Siakam scored 21 points and Serge Ibaka had 15 points and a season-high 15 rebounds as Toronto led from wire-to-wire and posted its 13th straight home win over the Pacers. The Raptors won for the 17th time in 18 games and extended their home winning streak to nine.

That streak will be tested when Giannis Antetokounmpo and the Bucks come north of the border Tuesday night, the first of three meetings between the teams down the stretch. The NBA leaders have won seven of eight heading into Monday's game at Washington.

Lowry's double-double was his 13th of the season. He's averaging 19.3 points and 10.8 assists over his current six-game run.

Toronto's largest lead was 49 points, its biggest of the season. The Raptors led by 40 in a home win over Utah on Dec. 1. The 46-point margin of victory surpassed a 36-point win over Charlotte on Nov. 18.

Matt Thomas scored all of his career-best 17 points in the fourth quarter, Terence Davis had 13 and Rondae Hollis-Jefferson 12. Chris Boucher had nine points and 11 rebounds.

Indiana's 81 points were the fewest by a Toronto opponent this season. Orlando scored 83 points in a home loss to the Raptors on Nov. 29.

Domantas Sabonis had 14 points and 11 rebounds, Aaron Holiday scored 14 points and Justin Holiday had 12 but the Pacers never recovered from an abysmal first quarter and lost for the first time in three games. Indiana has dropped seven of nine.

Pacers guard Victor Oladipo sat out because of back spasms, with Aaron Holiday starting in his place. Oladipo left Friday's road win over the Knicks after three quarters because of a sore back, and didn't practice Saturday.

Friday was Oladipo's first game without a minutes restriction after he missed the first 47 games of the season while recovering from a ruptured tendon in his right knee.

The Pacers lost another guard with 9:54 remaining in the second quarter when Jeremy Lamb injured his left knee, landing awkwardly after being fouled by Davis on a fast-break drive. Lamb was able to shoot his free throws, but the Pacers immediately fouled to stop play and replace Lamb. He did not return.

The Pacers host Charlotte on Tuesday night.