The coronavirus forced another change in Major League Baseball’s schedule, bringing the league’s total to eight teams affected in the first nine days of the season.

Friday’s game between St. Louis and Milwaukee was postponed after two Cardinals players tested positive for the coronavirus.

The league announced the schedule change hours before the game was to be played. It said the postponement in Milwaukee is “consistent with protocols to allow enough time for additional testing and contact tracing to be conducted.”

The Cardinals said in a statement that they learned Thursday night about positive tests from samples collected Wednesday. Players and staff have been instructed to isolate in their hotel rooms in Milwaukee, and the club did not leave the hotel Friday for Miller Park.

The Brewers and Cardinals plan to resume their schedule Saturday night at Miller Park, pending results from the testing and contact tracing, and makeup Friday’s game as part of a doubleheader Sunday.

Two other games scheduled for Friday involving the Marlins, Nationals, Blue Jays and Phillies had already been postponed because of an outbreak among Miami players and two positive tests on Philadelphia’s coaching staff.

The Cardinals played in Minnesota on Tuesday and Wednesday before a scheduled day off Thursday. The Twins hosted Cleveland on Thursday night, and the Indians used the same visiting clubhouse as St. Louis.

It’s uncertain if the Indians and Twins will move forward with their scheduled game Friday night. Cleveland planned to hold a team meeting early in the afternoon to discuss the situation.

A week into its virus-shortened season of 60 games in 67 days, Major League Baseball is scrambling to adjust its schedule.

The Marlins haven’t played since Sunday, and Miami’s situation has also led to schedule changes for the New York Yankees and Baltimore Orioles.