Goran Dragic scored 23 points, Bam Adebayo had 14 points and 19 rebounds and the fifth-seeded Heat completed a first-round sweep, beating the Pacers 99-87 on Monday night. Tyler Herro had 16 points for the Heat, who made it out of the first round for the first time since 2016.
Victor Oladipo had 25 points and Myles Turner added 22 points and 14 rebounds for the Pacers, who have been bounced in the first round of the playoffs in five straight seasons.
Miami's bench outscored Indiana's depleted reserves 38-3.
Dragic's layup at the end of the third quarter gave the Heat an eight-point lead and the Pacers never mounted a serious comeback in the fourth.
Indiana cut the lead to 91-85 with 3 minutes left, but the Heat got three offensive rebounds on one possession before Herro scored on a driving layup.
The Heat set a franchise playoff record with 124 points in Game 3, but this time they won with defense.
Heat guard Jimmy Butler left the game in the first quarter with a left shoulder strain. He returned after halftime and finished with six points in 23 minutes, although he made a handful of big plays on defense.
Miami moves on to face the winner of the Magic-Bucks series. Top-seeded Milwaukee dropped the opener to Orlando but has won three straight and would close out the series with a win Wednesday.
The Pacers played the series without Domantas Sabonis.
The Heat held a 60-34 edge in rebounding.
T.J. Warren scored 21 points for Indiana.