On Sunday, the Indianapolis Colts face a third consecutive challenge - slowing down two-time MVP Aaron Rodgers and the Green Bay Packers' potent offense.
Ace this one, and Indy will be well on its way to claiming the title of NFL's stingiest defense.
First, they tried to contain reigning MVP Lamar Jackson. Then they contended with 2019 rushing champion Derrick Henry.
At the moment, the Colts (6-3) sit at the top of the class.
They're No. 1 in overall defense, No. 2 against the pass, No. 3 against the run, No. 4 in scoring defense and No. 6 in turnover differential. They're tied for second in interceptions with 11, have scored three touchdowns and had two safeties. And for the first time in years, it's the defense that has helped Indy grab a share of the AFC South lead.
While Rodgers remains the leader of the Packers (7-2), Coach Matt LaFleur has tried to alleviate some of the burden on his quarterback. Aaron Jones and Jamaal Williams have emerged as a dynamic duo out of the backfield, and Davante Adams is one of the league's top receivers.
Together, they have pushed Green Bay to the top of the NFC North and the Packers are the first team in NFL history to average 30 or more points per game while committing five or fewer turnovers through nine games.
The question is whether the Packers run defense will improve after allowing 337 yards rushing and two 100-yard runners over the past three games.
Green Bay and Indy both have strong offensive lines and it's reflected in the numbers. Indy has allowed a league-low nine sacks this season. The Packers have allowed 11, tied for the third-lowest total. And with Packers left tackle David Bakhtiari returning from a broken rib last week, both lines should be at full strength Sunday.