As heard on WHOW, Nick Madrigal had three hits, including his first major league homer, and Danny Mendick launched his first career grand slam as the Chicago White Sox beat the struggling Minnesota Twins 16-4 on Monday night.

Seven players had multiple hits for Chicago, which posted season highs in hits (18) and runs. The White Sox have won nine of their past 11 games, including four straight wins against Minnesota.

Dallas Keuchel (3-1) was the beneficiary, pitching seven innings and allowing three runs on seven hits.

J.A. Happ (2-2) was roughed up again by the White Sox. The left-hander permitted six runs in 3 2/3 innings and has given up 15 runs to Chicago in his past two starts.

Happ had allowed just six runs in his first five starts for the Twins after signing as a free agent in the offseason. His ERA has risen from 1.91 to 5.35 in the past two starts.

Josh Donaldson hit a two-run homer and Rob Refsnyder had four hits for Minnesota, which has lost seven of eight.

The White Sox have enjoyed facing left-handed pitching in 2021. They started the day with an .853 OPS against left-handers to lead the majors. St. Louis was second with an .814 mark.

Jose Abreu will miss the entire series with left ankle inflammation. Abreu was injured sliding into home plate Sunday. X-rays were negative and an MRI showed inflammation. La Russa said Abreu will possibly return for Friday night's game in New York after an off day on Thursday.

Chicago right-hander Lance Lynn (4-1, 1.30 ERA) will make his first start in Minnesota since he was traded from the Twins to the New York Yankees in 2018. Lynn earned a win against Minnesota in his last start on May 13 when he gave up just an unearned run in five innings. RHP Michael Pineda (2-2, 2.79) will start for the Twins. Pineda allowed three runs in 5 1/3 innings opposite Lynn that day.