Albert Pujols had two hits and scored twice as the St. Louis Cardinals beat the Miami Marlins 5-1 on Tuesday night.

Adam Wainwright (2-1) allowed one run and five hits in 5 2/3 innings with six strikeouts and two walks.

Tommy Edman tripled, singled and drove in two runs, and Paul Goldschmidt also had two hits for St. Louis.

Marlins' starter Jesus Luzardo allowed five runs and seven hits in 4 1/3 innings. Luzardo (0-1) struck out three and walked two.

Wainwright walked two in the first inning, then settled down after third baseman Nolan Arenado reached near the foul line to grab Avisail Garcia's hard grounder and made a long throw to Goldschmidt. The first baseman stretched to catch Arenado's throw and get Garcia and end the early Marlins threat.

Tyler O'Neill had an RBI single in the third before Pujols singled and raced home from first on Edman's triple to right-center.

Edman added a run-scoring single in the fifth.

Wainwright and Molina made their 307th start together, surpassing the Chicago White Sox battery of Red Faber and Ray Schalk for third most in a big league career.

Bryan De Cruz homered for Miami in the sixth. Wainwright was lifted after allowing Brian Anderson's two-out single.

Relievers T.J. McFarland and Ryan Helsley got the next seven outs around three hits and Giovanny Gallegos worked a perfect ninth.

Cardinals prospect Nolan Gorman homered for the seventh time in seven games for for Triple-A Memphis.

Miles Mikolas (1-0, 2.61 ERA) will start the second game of the series for the Cardinals on Wednesday against RHP Sandy Alcantara (1-0, 3.18).