Jose Ramirez hit his second grand slam of the season, connecting during a nine-run second inning as the Cleveland Guardians roughed up Dallas Keuchel and routed the sloppy Chicago White Sox 11-1 Wednesday in a doubleheader opener.

Cleveland won at home for the first time with its new name. The Guardians had lost their first three at Progressive Field this season.

The Guardians delivered eight straight hits off Keuchel (1-1), who allowed a career-high 10 runs and 10 hits, before the former Cy Young Award winner was pulled with no outs in the second.

Chicago didn't help its left-hander too much, either, making four errors in the first two innings -- three by All-Star shortstop Tim Anderson -- that contributed to a pair of unearned runs.

Ramirez then had an RBI double in a 2-1 victory as the Cleveland Guardians swept a doubleheader from the Chicago White Sox on Wednesday.

Former Tigers and Blue Jays outfielder Anthony Gose (1-0) retired all five batters he faced in the nightcap, striking out four, for his first big league victory. Triston McKenzie allowed one run in 4 1/3 innings before giving way to Gose.

Ramirez and Oscar Mercado both had RBI doubles off White Sox starter Jimmy Lambert (0-2). Emmanuel Clase worked a 1-2-3 ninth for Cleveland's first save this season.

Mercado had three hits, Myles Straw scored three runs, and Ramirez and Naylor each had two hits for Cleveland. Second baseman Gabriel Arias made his major league debut in the first game and singled in the second.

Games between the White Sox and Cleveland on Monday and Tuesday were postponed by rain and cold, prompting a traditional doubleheader to be added to the schedule.

Dylan Cease (2-0, 1.69 ERA) has struck out 16 over 10 2/3 innings in his first two outings. Zach Plesac (0-1, 1.64 ERA) owns a six-start winless streak, going 0-3 with a 4.19 ERA.