Cedric Mullins and Tyler Nevin each homered and Kyle Bradish struck out 11 over seven strong innings, leading the Baltimore Orioles to a 5-3 victory over the St. Louis Cardinals on Tuesday night.

Mullins also added three singles and a stolen base in a 4-for-5 night and Anthony Santander had three hits, including a RBI double.

It was the Orioles' first time playing at the new Busch Stadium, which opened in 2006.

But the Cardinals were the ones to have a historic moment when Harrison Bader hit an inside-the-park home run in the sixth - the first for St. Louis at the current Busch Stadium and first for the Cardinals at home since 1985. The ball hit the wall in center and caromed toward left field away Mullins. Bader raced around the bases behind Yadier Molina, who had doubled, and scored standing up without a throw.

Fernando Vina was the last Cardinal to hit an inside-the-park HR, Oct. 2, 2001, in Milwaukee. There've been two other inside-the-parkers in the current Busch Stadium by opposing teams. The last Cardinal to do it at home was Vince Coleman on May 21, 1985, at Busch Stadium II.

Bradish (1-1) pitched seven innings for his longest outing this season and his first career win.

Bradish gave up four hits, including the homer to Bader. A double play in the first two innings helped him work around two singles. He was glad he was allowed to go back out in the seventh.

The Cardinals optioned SS Paul DeJong to Triple-A Memphis. The 28-year-old was an All-Star in 2019 when he hit 30 homers. He is hitting .130. in 24 games this season, with one home run, seven RBIs and 25 strikeouts in 77 at-bats.

Spenser Watkins (0-0, 3.22 ERA) will be making his first career outing against St. Louis. He did not factor in the decision in his last start, a 5-3 Orioles victory over Minnesota. The Cardinals will put up RHP Miles Mikolas (2-1, 1.53), who went 5 2/3 innings giving up seven hits but just one run against the San Francisco Giants in a 7-1 win.