In a game heard on WHOW, Luis Robert hit a two-run homer in the 10th inning after Johnny Cueto's impressive Chicago debut, and the White Sox defeated the Kansas City Royals 5-3 on Monday night in the opener of a five-game series.
Yasmani Grandal also had a two-run shot for the White Sox, who squandered a 3-0 lead in the eighth.
The 36-year-old Cueto pitched six shutout innings in his first major league start this season after getting promoted from Triple-A Charlotte. He allowed just two hits and two walks, striking out seven. Only one runner reached second base against him.
Ryan Burr (1-1) worked a scoreless ninth and Liam Hendriks earned his 10th save in 13 tries.
Barlow got five outs without giving up a hit until Robert went deep.
Brad Keller also was solid for Kansas City. He allowed three runs and eight hits in seven innings - with many of the hits coming on soft contact.
The White Sox got their first run on a sacrifice fly by Andrew Vaughn in the third. Adam Engel led off with a fly ball that dropped between left fielder Andrew Benintendi and center fielder Michael A. Taylor. Engel then stole second and scored on Vaughn's fly to right.
Grandal made it 3-0 when he lined an 0-2 pitch into the right-field bullpen. He drove in Robert, who extended his hitting streak to a career-high 14 games with an infield single.
The Royals tied it in the eighth against Kendall Graveman. Whit Merrifield lined a two-run double off the wall in left-center. He went to third on the throw home and scored on a single by Benintendi.
The White Sox will send RHP Dylan Cease (3-1, 3.55 ERA) to the mound in the opener and wait until after that game to determine who gets the ball for the nightcap. Tony La Russa said it's possible RHP Lucas Giolito (2-1, 2.70) could return from the COVID-19 injured list.
The Royals will have Jonathan Heasley (0-1, 2.70 ERA) pitch one game and Brady Singer (0-0, 6.35) the other. Kansas City manager Mike Matheny had not announced the order.