Jake Burger hit a game-ending RBI single in the 12th inning, and the banged-up Chicago White Sox topped the Chicago Cubs 5-4 on Sunday in a wild finale to the season series between the crosstown rivals.

Danny Mendick opened the White Sox 12th as the automatic runner, and he advanced on Andrew Vaughn's grounder to second against Robert Gsellman (0-2). Burger then pulled Gsellman's next pitch over a five-man infield for the winning hit.

Matt Foster (1-0) got three outs for the win for a struggling White Sox team that lost shortstop Tim Anderson to a right groin strain in the fifth. Anderson got hurt while making a play on P.J. Higgins' grounder back up the middle.

The Cubs opened a 3-1 lead with two runs in the 10th on reliever Reynaldo Lopez's throwing error and Christopher Morel's RBI single. Morel also robbed Burger of extra bases with a leaping grab in center with a runner on first in the eighth.

The White Sox responded with two runs in the bottom half of the 10th. Vaughn had a sacrifice fly and Jose Abreu tied it at 3 with an RBI single to center.

Rivas hit a sacrifice fly in the 11th for the Cubs, but Engel tied it again with an RBI single.

The Cubs wasted a terrific start by Marcus Stroman, who pitched seven innings of three-hit ball. Stroman helped himself with a pair of solid defensive plays. First, he snared Vaughn's comebacker in the fourth and threw him out at first. Then he jumped on Mendick's sacrifice attempt and cut down Harrison at third for the first out of the sixth.

The White Sox trailed 1-0 before pinch-runner AJ Pollock scored on David Robertson's wild pitch in the ninth. With two out and a runner on third, Josh Harrison bounced out to Nico Hoerner at shortstop.

The unearned run that scored on Burger's error was the only blemish on Dylan Cease's line. The right-hander allowed two hits, struck out five and walked four.