Luke Voit hit a two-run homer and a three-run double as the San Diego Padres rallied from a five-run deficit to hand the Chicago Cubs their eighth straight loss, 12-5 on Tuesday night.
The Padres trailed 5-0 when Cubs starter Kyle Hendricks was pulled after allowing a double to Jake Cronenworth to start the sixth inning. Voit homered off reliever Chris Martin to spark a four-run sixth, and his double off Mychal Givens gave the Padres the lead for good at 7-5 and highlighted a six-run seventh.
The Padres, who entered Tuesday's game tied with the Dodgers for first place in the NL West, have won six of eight. The Cubs' skid is their longest since since losing 12 in a row from Aug. 5-16, 2021.
Willson Contreras homered twice, drove in three runs and scored three times on a 3-for-4 night for the Cubs. He leads major league catchers with 12 homers.
The Padres' rally took left-hander Sean Manaea off the hook. He was tagged for five runs on eight hits in four-plus innings. Kyle Tyler (1-0) pitched two scoreless innings in relief.
Nomar Mazara drove in three runs with singles in the sixth and seventh. Jorge Alfaro hit his fourth homer in the eighth off left-hander Eric Stout.
Hendricks, pitching for the first time since June 1 because of shoulder fatigue, allowed one hit over the first four innings but needed a strikeout of Trent Grisham with runners at first and second to end the fifth.
LHP Ryan Weathers will face the Cubs Wednesday. Weathers is 4-7 with a 5.32 ERA at Triple-A El Paso.
Cubs RHP Caleb Kilian will promote from Triple-A Iowa to face the Padres. Kilian allowed three runs in five innings of a 7-4 loss to St. Louis in his major league debut on June 4.