In a game heard on WHOW, rookie Nick Pratto hit two home runs to highlight a career-high four-hit performance and the Kansas City Royals sent the Chicago White Sox to their fifth straight loss, 9-7 on Tuesday night.

White Sox manager Tony La Russa missed the game because of an unspecified medical issue. The team said the 77-year-old Hall of Famer was out on the recommendation of his doctors and would undergo further testing Wednesday.

La Russa's absence was announced about one hour before the first pitch. He showed no signs of health trouble during his pregame session with reporters. Bench coach Miguel Cairo took over as Chicago fell for the 10th time in its last 12 games since moving to a season-high five games over .500 on Aug. 16.

Gavin Sheets homered twice and drove in five runs for the White Sox.

Salvador Perez and Michael A. Taylor each homered and drove in three runs for the Royals. Pratto added a double and also had three RBIs.

Pratto hit solo home runs in each of his first two at-bats against Lucas Giolito (10-8), and his single off reliever Tanner Banks sparked a two-run sixth. Pratto hit a ground-rule double off Jake Diekman to score Ryan O'Hearn in the seventh.

Pratto is 8 for 17 with four doubles, three homers and 10 RBIs in his last four games. This marked the first multi-homer game of Pratto's career.

White Sox OF Luis Robert (left wrist) missed his fourth consecutive start due to lingering discomfort. 

3B Yoan Moncada (left hamstring strain) fielded grounders before Tuesday's game. Moncada is eligible to return from the 10-day injured list Sept. 5. 

The Royals will start LHP Kris Bubic (2-9, 5.62) on Wednesday. Bubic allowed a season-high six earned runs in four innings in a 13-5 loss Friday to the Padres.

White Sox RHP Lance Lynn (3-5, 5.00) will be activated from the bereavement list. Lynn allowed two runs in six innings of a 4-3 loss Thursday to the Orioles.