The Chicago White Sox watched Tony La Russa step down as manager, and then beat the Minnesota Twins 3-2 on Monday night behind Johnny Cueto's seven effective innings.

Josh Harrison hit a two-run homer in Chicago's fourth win in five games. Cueto (8-10) stopped a personal four-game slide, and Liam Hendriks got three outs for his 37th save.

Minnesota dropped to 9-19 in its last 28 games. Gio Urshela hit a two-run homer, and Bailey Ober pitched five innings of two-hit ball.

The game was tied at 2 before Carlos Perez drove in AJ Pollock with a two-out single against Griffin Jax (7-4) in the seventh. It was Perez's second career hit and first RBI.

The Twins loaded the bases with two out in the ninth, but Hendriks struck out Mark Contreras swinging to close it out.

Minnesota jumped in front in the first. Nick Gordon hit a two-out double and scored on Urshela's 13th homer, a drive to right on a 1-1 pitch.

But that was it for the Twins against Cueto, who struck out four and walked none. The right-hander was shaken up after fielding Matt Wallner's two-out infield single in the seventh, but he got Gilbert Celestino to bounce to third on his next pitch.

Chicago rallied in the second. With Pollock aboard on a one-out single, Harrison's drive traveled just over the wall in left for his seventh homer.