Anthony Edwards had season highs with 37 points and 11 assists and the Minnesota Timberwolves broke the franchise record for points in a game, routing the Chicago Bulls 150-126 on Sunday night.
D'Angelo Russell added 28 points after missing two games and Minnesota made a season-high 23 pointers to roll past Chicago despite missing four regulars.
Rudy Gobert missed his second straight game because of a sprained left ankle. Karl-Anthony Towns (right calf strain) and top reserves Jordan McLaughlin (left calf strain) and Taurean Prince (right shoulder) also sat out.
Starting a four-game trip, Chicago lost its fourth straight and sixth in eight games. It is the fourth-most points the Bulls have ever given up in regulation; the most since allowing 152 to Detroit on Nov. 3, 1982.
Nikola Vucevic added 23 points and Zach LaVine had 22.
Edwards scored six points in a 9-1 surge for a 106-89 lead late in the third quarter. But Edwards saved his best shot of the quarter for a buzzer-beater.
With 2.1 seconds left, he stole an inbounds pass on the logo at center court, continued right and made a 32-foot pull-up jumper. As the ball went through the hoop to make it 113-97, Edwards turned to face the crowd and, after a couple of seconds of basking with a huge smile, began to high-five the fans.
Russell made seven of his eight first-half shots, including 6 of 7 from deep. That included a 34-foot desperation heave from the logo early in the second quarter as the shot clock expired.
The Bulls are at Miami on Tuesday night.