Keaton Winn worked four solid innings of relief Tuesday night to help the San Francisco Giants to an 11-3 win over the St. Louis Cardinals.

Mike Yastrzemski and Patrick Bailey homered and Michael Conforto added four hits and three RBIs to pace a balanced attack.

The Giants have won five straight road games and six of their last eight games overall. San Francisco won the first two games of the three-game set and claimed just their third series in St. Louis in 10 tries since 2013.

St. Louis lost for the ninth time in the 11 games. The Cardinals fell to 27-41 overall, the team's worst start sing opening the 1978 campaign 24-44.

San Francisco's Luke Jackson (1-0) picked up the win with an inning of scoreless relief. Starter Alex Cobb allowed two runs on five hits over four innings.

Flaherty (3-5) allowed six runs on 10 hits over 4 1/3 innings.

Wade Jr. got into a shouting match with Flaherty after the top of the fourth inning. Wade had to be held back by teammates. Benches and bullpens emptied, but no punches were thrown and there were no ejections.

St. Louis has spent the last 49 days in last place in the NL Central after winning the division last season.

Anthony DeSclafani (4-6, 3.89) will face LHP Jordan Montgomery (3-7, 3.88) in the finale of the three-game set on Wednesday afternoon. Montgomery tossed six scoreless innings in his last outing, a 7-4 win over Cincinnati on Friday.