Connor Joe and Oneil Cruz drove in runs in the ninth inning, lifting the Pittsburgh Pirates to a 2-1 victory over the St. Louis Cardinals on Tuesday night.

Colin Holderman (2-0) gave up two hits but no runs in the eighth and David Bednar earned his 14th save by pitching the ninth despite giving up a first-pitch leadoff home run to Nolan Gorman.

Bednar has converted 13 straight save opportunities and his 75 saves are the seventh-most in team history.

Both starters were splendid and neither gave up a run.

Miles Mikolas threw 84 pitches and gave up one hit over seven innings, striking out six and walking one. He took a no-hitter into the seventh but lost it when Bryan Reynolds led off with a triple off the wall in dead center.

Mikolas retired the first 16 batters he faced before walking Yasmani Grandal on a full count with one out in the sixth.

Pittsburgh rookie Paul Skenes pitched 6 1/3 innings and threw a career-high 103 pitches, 74 for strikes. He allowed five hits with eight strikeouts and no walks.

The Cardinals began the fifth with back-to-back singles by Nolan Arenado and Matt Carpenter. Skenes pitched out of the jam by striking out two before getting a groundout.

The top overall draft pick last season, Skenes, 22, has not given up more than three runs in any of his first six career starts.

Ryan Helsley (2-3) loaded the bases to start the ninth. Jack Suwinski drew a walk and Andrew McCutchen singled before Helsley walked Reynolds on four pitches. Joe grounded to shortstop but Suwinski scored.

Cruz's sacrifice fly drove in McCutchen.

Pirates LHP Bailey Falter (3-3, 3.69 ERA) allowed five runs in four-plus innings and lost an 11-7 decision against the Dodgers last Thursday.

Cardinals RHP Sonny Gray (7-4, 3.21 ERA) pitched his shortest outing of the season at 4 2/3 innings and issued a season-high four walks in a 3-2 home loss to Colorado.