Wilyer Abreu singled off the Green Monster to drive in the winning run in the bottom of the 10th inning, and the Boston Red Sox rallied for a 5-4 walk-off victory over the St. Louis Cardinals on Sunday in the opener of a day-night doubleheader.

Rafael Devers hit his first homer for the Red Sox, who won their fourth straight.

Boston had tied it with two runs on a hit and four walks against closer Ryan Helsley in the ninth. Romy Gonzalez had an RBI double in the inning.

Pedro Pagés replaced catcher Iván Herrera after he came out with left knee inflammation and drove in three runs with two doubles for the Cardinals.

Pagés picked Connor Wong off first to end the seventh before his two-run double off the Monster pushed the Cardinals ahead 4-2 in the eighth. He also threw out Gonzalez attempting to steal second in the seventh.

The game was the makeup of Saturday’s rainout.

Alex Bregman hit a three-run homer and tied a career high with six RBIs, Rafael Devers went 4 for 4 and drove in three runs, and the Boston Red Sox rolled to an 18-7 win and a doubleheader sweep of the St. Louis Cardinals on Sunday night.

Wilyer Abreu added three RBIs for Boston, which finished with a season-best 22 hits and won its fifth straight. It was the 14th career four-hit game for Devers, who also scored four runs. Bregman had four hits for the 10th time, and Jarren Duran had three hits and scored three runs.

All that offense made for an easy night for Hunter Dobbins (1-0), who scattered five hits and gave up two runs over five innings to win his major league debut.

St. Louis starter Miles Mikolas (0-1) permitted nine runs - eight earned - and 11 hits in 2 2/3 innings. Thomas Saggaese hit a three-run homer in the ninth and Brendan Donovan had three hits and two RBIs for the Cardinals. St. Louis extended a team record with its ninth straight game getting at least 10 hits.

Matthew Liberatore (0-0, 4.50 ERA) will start as the Cardinals open a three-game series Monday in Pittsburgh.